Twitter Only Mutes 100 Keywords
To see why it’s not enough, you need to know exactly how keyword muting works. To start, ask yourself why @username muting even exists. The ability to mute or block an account was already a Twitter feature. You might think that if you had blocked an account, Twitter would automatically mute any tweets containing mentions of the blocked account. That would be the sane implementation. Yet that is not the actual implementation. Twitter does not automatically mute tweets that mention accounts you’ve blocked, so you have to waste keyword mutes on those accounts.
The other major problem with Twitter keyword muting is that it only matches full words or phrases. It doesn’t match prefixes at all. In other words, Twitter does not automatically mute plural or possessive forms of your keywords.