Cappuccino and Objective-J
It’s like Cocoa and Objective-C for the Web:
With Cappuccino, you don’t need to know HTML. You’ll never write a line of CSS. You don’t ever have interact with DOM. We only ask developers to learn one technology, Objective-J, and one set of APIs. Plus, these technologies are implementations of well known and well understood existing ones. Developers can leverage decades of collective experience to really accelerate the pace of building rich Web applications.